The plot centers on Zuckerman's return home to New York after eleven years in New England. The purpose of Zuckerman's journey, which he takes the week before the 2004 U.S. presidential election, is for him to undergo a medical procedure that might cure his incontinence. While in New York, Zuckerman meets Amy Bellette, whom he had last encountered during a visit to the writer E.I. Lonoff's house in December, 1956, as depicted in Roth's novel The Ghost Writer. Zuckerman also agrees to a housing swap with a young writing couple, Billy Davidoff and Jamie Logan, and quickly becomes attracted to Logan. In his hotel room at night, Zuckerman writes a play, He and She, composed of imagined conversations between him and Logan.