The end of the 15th and the dawn of the 16th century ... Italy was torn by wars with the French kings, by internal struggles and rivalry between noble families for power and patronage. Savonarola was excommunicated from the Church, hanged and burned; Machiavelli, the diplomat, defends the Florentine republic from the assaults of the papal son Cesare Borgia; Leonardo creates the masterpiece "The Last Supper" and explores the magic of numbers and the enigma of geometric bodies with the help of the Franciscan mathematician Luca Pacioli. Francesco Fioretti combines the intriguing criminal plot with an impressive picture of the era and a bright portrait of Leonardo da Vinci's encyclopedic genius.